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Direct flights from Knoxville to Chicago

Airlines Schedules

TYS - ORD route map All flights from TYS to ORD non-stop. There are direct flights from Mc Ghee Tyson (TYS), Tennessee, USA to Chicago O Hare International (ORD), Illinois, USA with American Airlines and United Airlines. 65 weekly departures are currently scheduled on this route. Departure times range from 06:00 to 20:52 depending on the schedule period. The flight distance is 477 miles (767 km). Flight time ranges from 1 hour and 55 minutes to 2 hours and 26 minutes.

TYS
Mc Ghee Tyson
USAKnoxville , USA
ORD
Chicago O Hare
USAChicago , USA
TYS
Mc Ghee Tyson
USAKnoxville , USA
Chicago O Hare
USAChicago , USA
ORD
Flight time 1h 55min to 2h 26min
Updated Sep 28, 2026
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Airlines with non-stop routes:

American Airlines oneworld

Departure times vary between 06:00 and 20:52
S
M
T
W
T
F
S
Sun
Mon
Tue
Wed
Thu
Fri
Sat
37 flights/week
37 flights/week

United Airlines Star Alliance

Departure times vary between 06:00 and 18:03
S
M
T
W
T
F
S
Sun
Mon
Tue
Wed
Thu
Fri
Sat
28 flights/week
28 flights/week
Weekday-labels: HAS FLIGHTS UPCOMING NO FLIGHTS
View all flight dates
Flight schedule from Knoxville to Chicago with American Airlines

This is a weekly direct flight schedule for American Airlines. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.

 
Flight
Mon
Oct 26
Tue
Oct 27
Wed
Oct 28
Thu
Oct 29
Fri
Oct 30
Sat
Oct 31
Sun
Nov 1
AA4751
07:30
07:30
07:30
07:30
07:30
07:30
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AA4509
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07:56
AA5408
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11:34
AA4229
11:35
11:35
11:35
11:35
11:35
11:35
16:59
AA3501
17:07
16:38
16:38
16:38
17:07
16:48
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AA3547
18:55
18:55
18:55
18:55
18:55
18:55
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AA3653
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----
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20:52

The timetable & schedule information was updated at 2026-09-28

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Flight schedule from Knoxville to Chicago with United Airlines

This is a weekly direct flight schedule for United Airlines. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.

 
Flight
Mon
Oct 26
Tue
Oct 27
Wed
Oct 28
Thu
Oct 29
Fri
Oct 30
Sat
Oct 31
Sun
Nov 1
UA5524
06:45
06:45
06:45
06:45
06:45
06:45
06:45
UA4581
10:43
10:45
10:45
10:43
10:43
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10:33
UA3716
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10:51
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UA4460
13:51
13:56
13:56
13:51
13:51
13:54
13:51
UA5478
17:40
17:40
17:40
17:40
17:40
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17:40
UA3532
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----
----
----
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17:40
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The timetable & schedule information was updated at 2026-09-28

RETURN SCHEDULE
CHECK PRICES
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Knoxville to Chicago scheduled departures

Select a date to see every published non-stop departure between TYS and ORD.

Friday
Fri
Oct 23
8 flights(8)
Saturday
Sat
Oct 24
8 flights(8)
Sunday
Sun
Oct 25
8 flights(8)
Monday
Mon
Oct 26
8 flights(8)
Tuesday
Tue
Oct 27
8 flights(8)
Wednesday
Wed
Oct 28
8 flights(8)
Thursday
Thu
Oct 29
8 flights(8)
Time
Airline
Flight
06:00
United Airlines United Airlines
UA1553
07:30
American Airlines American Airlines
AA4751
10:42
United Airlines United Airlines
UA1577
11:35
American Airlines American Airlines
AA4229
13:55
United Airlines United Airlines
UA4548
17:07
American Airlines American Airlines
AA3501
18:03
United Airlines United Airlines
UA5869
18:55
American Airlines American Airlines
AA3547
06:00
United Airlines United Airlines
UA1553
07:30
American Airlines American Airlines
AA4751
10:42
United Airlines United Airlines
UA1577
11:35
American Airlines American Airlines
AA4229
13:55
United Airlines United Airlines
UA4548
16:38
American Airlines American Airlines
AA3501
18:03
United Airlines United Airlines
UA5869
18:55
American Airlines American Airlines
AA3547
06:45
United Airlines United Airlines
UA5524
07:30
American Airlines American Airlines
AA4751
10:43
United Airlines United Airlines
UA4581
11:35
American Airlines American Airlines
AA4229
13:51
United Airlines United Airlines
UA4460
17:07
American Airlines American Airlines
AA3501
17:40
United Airlines United Airlines
UA5478
18:55
American Airlines American Airlines
AA3547
06:45
United Airlines United Airlines
UA5524
07:30
American Airlines American Airlines
AA4751
10:43
United Airlines United Airlines
UA4581
11:35
American Airlines American Airlines
AA4229
13:51
United Airlines United Airlines
UA4460
17:07
American Airlines American Airlines
AA3501
17:40
United Airlines United Airlines
UA5478
18:55
American Airlines American Airlines
AA3547
06:45
United Airlines United Airlines
UA5524
07:30
American Airlines American Airlines
AA4751
10:45
United Airlines United Airlines
UA4581
11:35
American Airlines American Airlines
AA4229
13:56
United Airlines United Airlines
UA4460
16:38
American Airlines American Airlines
AA3501
17:40
United Airlines United Airlines
UA5478
18:55
American Airlines American Airlines
AA3547
06:45
United Airlines United Airlines
UA5524
07:30
American Airlines American Airlines
AA4751
10:45
United Airlines United Airlines
UA4581
11:35
American Airlines American Airlines
AA4229
13:56
United Airlines United Airlines
UA4460
16:38
American Airlines American Airlines
AA3501
17:40
United Airlines United Airlines
UA5478
18:55
American Airlines American Airlines
AA3547
06:45
United Airlines United Airlines
UA5524
07:30
American Airlines American Airlines
AA4751
10:43
United Airlines United Airlines
UA4581
11:35
American Airlines American Airlines
AA4229
13:51
United Airlines United Airlines
UA4460
16:38
American Airlines American Airlines
AA3501
17:40
United Airlines United Airlines
UA5478
18:55
American Airlines American Airlines
AA3547
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TYS-ORD flight route
Route map from Knoxville, TYS to Chicago, ORD. The distance is 477 miles or 767 km.
Knoxville - Chicago direct flight map
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TYS - ORD route facts

  • Distance
    477 miles (767 km)
  • Flight time
    1 hour and 55 minutes to 2 hours and 26 minutes
  • Airlines
    American Airlines American Airlines
    United United
  • Airline alliances
    oneworld Star Alliance
  • Cabins
    Economy First
  • Hub airports
    American Airlines: ORD
    United Airlines: ORD (Largest hub.)
  • Arrival terminals
    American Airlines: Terminal 3
    United Airlines: Terminal 1 and Terminal 2
  • Aircraft
    American Airlines: Canadair (Bombardier) Regional Jet 700 and Challenger 870, Embraer 170 and Embraer 175
    United Airlines: Airbus A320, Embraer 175 (Enhanced Winglets), Canadair (Bombardier) Regional Jet 550, Airbus A319 and Canadair (Bombardier) Regional Jet 200

Route FAQ

American Airlines and United Airlines operate non-stop flights from TYS to ORD with 65 weekly departures.

Scheduled flight time from TYS to ORD ranges from 1 hour and 55 minutes to 2 hours and 26 minutes. The route covers 477 miles (767 km).

65 weekly departures are currently scheduled on this route, with published departure times ranging from 06:00 to 20:52 depending on the schedule period.

Arrival terminals: American Airlines: Terminal 3 and United Airlines: Terminal 1 and Terminal 2.

Economy and First are currently scheduled on non-stop flights for this route.
Direct flights from Knoxville to IL, USA
From Knoxville to Chicago

MDW Chicago Midway International
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