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Direct flights from Tampa to Knoxville

Airlines Schedules

TPA - TYS route map All flights from TPA to TYS non-stop. There are direct flights from Tampa International (TPA), Florida, USA to Mc Ghee Tyson (TYS), Tennessee, USA with Southwest Airlines. 1 weekly departure are currently scheduled on this route. Departure times range from 12:40 to 17:10 depending on the schedule period. The flight distance is 551 miles (887 km). Flight time ranges from 1 hour and 50 minutes to 1 hour and 55 minutes.

TPA
Tampa
USATampa , USA
TYS
Mc Ghee Tyson
USAKnoxville , USA
TPA
Tampa
USATampa , USA
Mc Ghee Tyson
USAKnoxville , USA
TYS
Flight time 1h 50min to 1h 55min
Updated Aug 3, 2026
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Airlines with non-stop routes:

Southwest Airlines Low-cost carrier

Departure times vary between 12:40 and 17:10
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From 21/11
From 21/11
Weekday-labels: HAS FLIGHTS UPCOMING NO FLIGHTS
View all flight dates
Flight schedule from Tampa to Knoxville with Southwest Airlines

This is a weekly direct flight schedule for Southwest Airlines. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.

 
Flight
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Nov 16
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WN4205
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12:40
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The timetable & schedule information was updated at 2026-08-03

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Tampa to Knoxville scheduled departures

Select a date to see every published non-stop departure between TPA and TYS.

Thursday
Thu
Sep 03
0 flights(0)
Friday
Fri
Sep 04
0 flights(0)
Saturday
Sat
Sep 05
0 flights(0)
Sunday
Sun
Sep 06
0 flights(0)
Monday
Mon
Sep 07
0 flights(0)
Tuesday
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Sep 08
0 flights(0)
Wednesday
Wed
Sep 09
0 flights(0)
Time
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Flight
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TPA-TYS flight route
Route map from Tampa, TPA to Knoxville, TYS. The distance is 551 miles or 887 km.
Tampa - Knoxville direct flight map
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TPA - TYS route facts

  • Distance
    551 miles (887 km)
  • Flight time
    1 hour and 50 minutes to 1 hour and 55 minutes
  • Airline
    Southwest Southwest
  • Airline alliances
    Low-cost carrier
  • Cabins
    Economy
  • Aircraft
    Boeing 737-800 (winglets) Passenger/BBJ2 and Boeing 737MAX 8 Passenger

Route FAQ

Southwest Airlines operates non-stop flights from TPA to TYS with 1 weekly departure.

Scheduled flight time from TPA to TYS ranges from 1 hour and 50 minutes to 1 hour and 55 minutes. The route covers 551 miles (887 km).

1 weekly departure are currently scheduled on this route, with published departure times ranging from 12:40 to 17:10 depending on the schedule period.

Economy are currently scheduled on non-stop flights for this route.
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