Direct flights from Panama City to Santa Cruz

Airlines Schedules

PTY - VVI route map All flights from PTY to VVI non-stop. There are direct flights from Tocumen International (PTY), Panama to Santa Cruz (VVI), Bolivia with Copa Airlines. 11 weekly departures are currently scheduled on this route. Departure times range from 16:05 to 22:00 depending on the schedule period. The flight distance is 2164 miles (3482 km). Flight time ranges from 4 hours and 52 minutes to 5 hours and 8 minutes.

PTY
Tocumen

Panama City , Panama

VVI
Santa Cruz

Santa Cruz , Bolivia

PTY

Tocumen

Panama City , Panama

Santa Cruz
Bolivia

Santa Cruz , Bolivia

VVI

Flight time 4h 52min to 5h 8min

Updated Oct 12, 2026

CHANGE DIRECTION

Airlines with non-stop routes:

Copa Airlines Star Alliance

Departure times vary between 16:05 and 22:00 • From Terminal 2

Sun

Mon

Tue

Wed

Thu

Fri

Sat

11 flights/week

Weekday-labels: HAS FLIGHTS UPCOMING NO FLIGHTS

View all flight dates

Flight schedule from Panama City to Santa Cruz with Copa Airlines

This is a weekly direct flight schedule for Copa Airlines. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.

Flight

Mon

Nov 9

Tue

Nov 10

Wed

Nov 11

Thu

Nov 12

Fri

Nov 13

Sat

Nov 14

Sun

Nov 15

CM127

16:40

CM221

21:45

----

21:45

----

21:45

The timetable & schedule information was updated at 2026-10-12

RETURN SCHEDULE

CHECK PRICES

SPONSORED AD

Panama City to Santa Cruz scheduled departures

Select a date to see every published non-stop departure between PTY and VVI.

Select date to show departures:

Friday

Fri

Nov 06

2 flights(2)

Saturday

Sat

Nov 07

1 flights(1)

Sunday

Sun

Nov 08

2 flights(2)

Monday

Mon

Nov 09

2 flights(2)

Tuesday

Tue

Nov 10

2 flights(2)

Wednesday

Wed

Nov 11

2 flights(2)

Thursday

Thu

Nov 12

1 flights(1)

Time

Airline

Flight