Direct flights from Panama City to Medellin
All flights from PTY to MDE non-stop. There are direct flights from Tocumen International (PTY), Panama to Jose Maria Cordova (MDE), Colombia with Copa Airlines. 53 weekly departures are currently scheduled on this route. Departure times range from 06:05 to 22:00 depending on the schedule period. The flight distance is 327 miles (526 km). Flight time ranges from 1 hour and 18 minutes to 1 hour and 32 minutes.
Panama City
, Panama
Medellin
, Colombia
Flight schedule from Panama City to Medellin with Copa Airlines
This is a weekly direct flight schedule for Copa Airlines. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.
Flight
The timetable & schedule information was updated at 2026-08-24
Panama City to Medellin scheduled departures
Select a date to see every published non-stop departure between PTY and MDE.
PTY - MDE route facts
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Distance327 miles (526 km)
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Flight time1 hour and 18 minutes to 1 hour and 32 minutes
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Airline Copa Airlines
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Airline alliancesStar Alliance
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CabinsEconomy Business
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Hub airportsPTY
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AircraftBoeing 737-800 Passenger, Boeing 737MAX 8 Passenger, Boeing 737MAX 9 Passenger and Boeing 737-700 Passenger
Route FAQ
Direct flights from Panama City to Colombia
From Panama City to Bogota
BOG El Dorado International Airport
From Panama City to Cucuta
CUC Camilo Daza International Airport
From Panama City to Cali
CLO Alfonso Bonilla Aragon International
From Panama City to Bucaramanga
BGA Palonegro
From Panama City to Armenia
AXM El Eden
From Panama City to Santa Marta
SMR Simon Bolivar
From Panama City to Pereira
PEI Matecana
From Panama City to San Andres Island
ADZ San Andres Island
From Panama City to Barranquilla
BAQ Ernesto Cortissoz
From Panama City to Cartagena
CTG Rafael Nunez
