Direct flights from New Orleans to Knoxville
All flights from MSY to TYS non-stop. There are direct flights from Louis Armstrong New Orleans International (MSY), Louisiana, USA to Mc Ghee Tyson (TYS), Tennessee, USA with American Airlines and Southwest Airlines. once a week Departure times range from 08:05 to 14:30 depending on the schedule period. The flight distance is 544 miles (875 km). Flight time is about 2 hours.
New Orleans
, USA
Flight schedule from New Orleans to Knoxville with American Airlines
This is a weekly direct flight schedule for American Airlines. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.
Flight
The timetable & schedule information was updated at 2026-09-21
Flight schedule from New Orleans to Knoxville with Southwest Airlines
This is a weekly direct flight schedule for Southwest Airlines. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.
Flight
The timetable & schedule information was updated at 2026-09-21
New Orleans to Knoxville scheduled departures
Select a date to see every published non-stop departure between MSY and TYS.
MSY - TYS route facts
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Distance544 miles (875 km)
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Flight time2 hours
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Airlines American Airlines Southwest
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Airline alliancesoneworld Low-cost carrier
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CabinsEconomy First
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AircraftAmerican Airlines: Embraer 175Southwest Airlines: Boeing 737MAX 8 Passenger
Route FAQ
Direct flights from New Orleans to TN, USA
From New Orleans to Nashville
BNA Nashville International
