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Direct flights from Minneapolis to Knoxville

Airlines Schedules

MSP - TYS route map All flights from MSP to TYS non-stop. There are direct flights from Minneapolis St Paul International (MSP), Minnesota, USA to Mc Ghee Tyson (TYS), Tennessee, USA with Delta Air Lines. 13 weekly departures are currently scheduled on this route. Departure times range from 13:10 to 19:55 depending on the schedule period. The flight distance is 796 miles (1281 km). Flight time ranges from 2 hours and 15 minutes to 2 hours and 19 minutes.

MSP
Minneapolis St Paul
USAMinneapolis , USA
TYS
Mc Ghee Tyson
USAKnoxville , USA
MSP
Minneapolis St Paul
USAMinneapolis , USA
Mc Ghee Tyson
USAKnoxville , USA
TYS
Flight time 2h 15min to 2h 19min
Updated Jul 13, 2026
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Airlines with non-stop routes:

Delta Air Lines SkyTeam

Departure times vary between 13:10 and 19:55 • From Terminal 1
S
M
T
W
T
F
S
Sun
Mon
Tue
Wed
Thu
Fri
Sat
13 flights/week
13 flights/week
Weekday-labels: HAS FLIGHTS UPCOMING NO FLIGHTS
View all flight dates
Flight schedule from Minneapolis to Knoxville with Delta Air Lines

This is a weekly direct flight schedule for Delta Air Lines. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.

 
Flight
Mon
Aug 10
Tue
Aug 11
Wed
Aug 12
Thu
Aug 13
Fri
Aug 14
Sat
Aug 15
Sun
Aug 16
DL5335
13:25
13:25
13:25
13:25
13:25
----
13:25
DL5527
19:45
19:45
19:45
19:45
19:45
19:45
19:45

The timetable & schedule information was updated at 2026-07-13

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Minneapolis to Knoxville scheduled departures

Select a date to see every published non-stop departure between MSP and TYS.

Wednesday
Wed
Aug 12
2 flights(2)
Thursday
Thu
Aug 13
2 flights(2)
Friday
Fri
Aug 14
2 flights(2)
Saturday
Sat
Aug 15
1 flights(1)
Sunday
Sun
Aug 16
2 flights(2)
Monday
Mon
Aug 17
2 flights(2)
Tuesday
Tue
Aug 18
2 flights(2)
Time
Airline
Flight
13:25
Delta Air Lines Delta Air Lines
DL5335
19:45
Delta Air Lines Delta Air Lines
DL5527
13:25
Delta Air Lines Delta Air Lines
DL5335
19:45
Delta Air Lines Delta Air Lines
DL5527
13:25
Delta Air Lines Delta Air Lines
DL5335
19:45
Delta Air Lines Delta Air Lines
DL5527
19:45
Delta Air Lines Delta Air Lines
DL5527
13:25
Delta Air Lines Delta Air Lines
DL5335
19:45
Delta Air Lines Delta Air Lines
DL5527
13:25
Delta Air Lines Delta Air Lines
DL5335
19:45
Delta Air Lines Delta Air Lines
DL5527
13:25
Delta Air Lines Delta Air Lines
DL5335
19:45
Delta Air Lines Delta Air Lines
DL5527
Departing from Minneapolis St Paul International
Departing from Minneapolis St Paul International. Copyright: Metropolitan Airports Commission
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MSP-TYS flight route
Route map from Minneapolis, MSP to Knoxville, TYS. The distance is 796 miles or 1281 km.
Minneapolis - Knoxville direct flight map
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MSP - TYS route facts

  • Distance
    796 miles (1281 km)
  • Flight time
    2 hours and 15 minutes to 2 hours and 19 minutes
  • Airline
    Delta Delta
  • Airline alliances
    SkyTeam
  • Cabins
    Economy First
  • Hub airports
    MSP
  • Departure terminals
    Terminal 1
  • Aircraft
    Canadair (Bombardier) Regional Jet 700 and Challenger 870 and Canadair (Bombardier) Regional Jet 900

Route FAQ

Delta Air Lines operates non-stop flights from MSP to TYS with 13 weekly departures.

Scheduled flight time from MSP to TYS ranges from 2 hours and 15 minutes to 2 hours and 19 minutes. The route covers 796 miles (1281 km).

13 weekly departures are currently scheduled on this route, with published departure times ranging from 13:10 to 19:55 depending on the schedule period.

Departure terminal: Terminal 1.

Economy and First are currently scheduled on non-stop flights for this route.
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