Direct flights from Chicago to Saint Louis
All flights from MDW to STL non-stop. There are direct flights from Chicago Midway International (MDW), Illinois, USA to Saint Louis Airport (STL), Missouri, USA with Southwest Airlines. 39 weekly departures are currently scheduled on this route. Departure times range from 05:40 to 23:00 depending on the schedule period. The flight distance is 252 miles (405 km). Flight time ranges from 1 hour and 10 minutes to 1 hour and 25 minutes.
Chicago
, USA
Flight schedule from Chicago to Saint Louis with Southwest Airlines
This is a weekly direct flight schedule for Southwest Airlines. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.
Flight
The timetable & schedule information was updated at 2026-07-12
Chicago to Saint Louis scheduled departures
Select a date to see every published non-stop departure between MDW and STL.
MDW - STL route facts
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Distance252 miles (405 km)
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Flight time1 hour and 10 minutes to 1 hour and 25 minutes
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Airline Southwest
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Airline alliancesLow-cost carrier
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CabinsEconomy
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Arrival terminalsTerminal 2
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AircraftBoeing 737-800 (winglets) Passenger/BBJ2, Boeing 737MAX 8 Passenger and Boeing 737-700 Passenger (Scimitar Winglets)
Route FAQ
Direct flights from Chicago to MO, USA
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