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Direct flights from Medellin to Guayaquil

Airlines Schedules

MDE - GYE route map All flights from MDE to GYE non-stop. There are direct flights from Jose Maria Cordova (MDE), Colombia to Simon Bolivar International (GYE), Ecuador with AVIANCA. 3 weekly departures are currently scheduled on this route. Departure time is 16:50. The flight distance is 653 miles (1051 km). Flight time ranges from 1 hour and 55 minutes to 2 hours.

MDE
Jose Maria Cordova
ColombiaMedellin , Colombia
GYE
Simon Bolivar
EcuadorGuayaquil , Ecuador
MDE
Jose Maria Cordova
ColombiaMedellin , Colombia
Simon Bolivar
EcuadorGuayaquil , Ecuador
GYE
Flight time 1h 55min to 2h 0min
Updated Oct 12, 2026
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Airlines with non-stop routes:

AVIANCA Star Alliance

Departs at 16:50
S
M
T
W
T
F
S
Sun
Mon
Tue
Wed
Thu
Fri
Sat
3 flights/week
3 flights/week
Weekday-labels: HAS FLIGHTS UPCOMING NO FLIGHTS
View all flight dates
Flight schedule from Medellin to Guayaquil with AVIANCA

This is a weekly direct flight schedule for AVIANCA. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.

 
Flight
Mon
Nov 9
Tue
Nov 10
Wed
Nov 11
Thu
Nov 12
Fri
Nov 13
Sat
Nov 14
Sun
Nov 15
AV8399
16:50
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16:50
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16:50
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The timetable & schedule information was updated at 2026-10-12

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Medellin to Guayaquil scheduled departures

Select a date to see every published non-stop departure between MDE and GYE.

Saturday
Sat
Nov 07
0 flights(0)
Sunday
Sun
Nov 08
0 flights(0)
Monday
Mon
Nov 09
1 flights(1)
Tuesday
Tue
Nov 10
0 flights(0)
Wednesday
Wed
Nov 11
1 flights(1)
Thursday
Thu
Nov 12
0 flights(0)
Friday
Fri
Nov 13
1 flights(1)
Time
Airline
Flight
16:50
AVIANCA AVIANCA
AV8399
16:50
AVIANCA AVIANCA
AV8399
16:50
AVIANCA AVIANCA
AV8399
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MDE-GYE flight route
Route map from Medellin, MDE to Guayaquil, GYE. The distance is 653 miles or 1051 km.
Medellin - Guayaquil direct flight map
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MDE - GYE route facts

  • Distance
    653 miles (1051 km)
  • Flight time
    1 hour and 55 minutes to 2 hours
  • Airline
    AVIANCA AVIANCA
  • Airline alliances
    Star Alliance
  • Cabins
    Economy Business
  • Hub airports
    MDE (Secondary hub.)
  • Aircraft
    Airbus A320 and Airbus A320neo

Route FAQ

AVIANCA operates non-stop flights from MDE to GYE with 3 weekly departures.

Scheduled flight time from MDE to GYE ranges from 1 hour and 55 minutes to 2 hours. The route covers 653 miles (1051 km).

3 weekly departures are currently scheduled on this route, departing at 16:50.

Economy and Business are currently scheduled on non-stop flights for this route.
Direct flights from Medellin to Ecuador
From Medellin to Quito

UIO Mariscal Sucre International
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