Which airport are you flying from?

Direct flights from Medellin to Guayaquil

Airlines Schedules

MDE - GYE route map All flights from MDE to GYE non-stop. There are direct flights from Jose Maria Cordova (MDE), Colombia to Simon Bolivar International (GYE), Ecuador with AVIANCA. 3 weekly departures are currently scheduled on this route. Departure time is 16:50. The flight distance is 653 miles (1051 km). Flight time ranges from 1 hour and 55 minutes to 2 hours.

MDE
Jose Maria Cordova
ColombiaMedellin , Colombia
GYE
Simon Bolivar
EcuadorGuayaquil , Ecuador
MDE
Jose Maria Cordova
ColombiaMedellin , Colombia
Simon Bolivar
EcuadorGuayaquil , Ecuador
GYE
Flight time 1h 55min to 2h 0min
Updated Aug 24, 2026
CHANGE DIRECTION

Airlines with non-stop routes:

AVIANCA Star Alliance

Departs at 16:50
S
M
T
W
T
F
S
Sun
Mon
Tue
Wed
Thu
Fri
Sat
3 flights/week
3 flights/week
Weekday-labels: HAS FLIGHTS UPCOMING NO FLIGHTS
View all flight dates
Flight schedule from Medellin to Guayaquil with AVIANCA

This is a weekly direct flight schedule for AVIANCA. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.

 
Flight
Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
Fri
Sep 25
Sat
Sep 26
Sun
Sep 27
AV8399
16:50
----
16:50
----
16:50
----
----

The timetable & schedule information was updated at 2026-08-24

RETURN SCHEDULE
CHECK PRICES
SPONSORED AD

Medellin to Guayaquil scheduled departures

Select a date to see every published non-stop departure between MDE and GYE.

Thursday
Thu
Sep 24
0 flights(0)
Friday
Fri
Sep 25
1 flights(1)
Saturday
Sat
Sep 26
0 flights(0)
Sunday
Sun
Sep 27
0 flights(0)
Monday
Mon
Sep 28
1 flights(1)
Tuesday
Tue
Sep 29
0 flights(0)
Wednesday
Wed
Sep 30
1 flights(1)
Time
Airline
Flight
16:50
AVIANCA AVIANCA
AV8399
16:50
AVIANCA AVIANCA
AV8399
16:50
AVIANCA AVIANCA
AV8399
SPONSORED AD
MDE-GYE flight route
Route map from Medellin, MDE to Guayaquil, GYE. The distance is 653 miles or 1051 km.
Medellin - Guayaquil direct flight map
SPONSORED AD
SPONSORED AD

MDE - GYE route facts

  • Distance
    653 miles (1051 km)
  • Flight time
    1 hour and 55 minutes to 2 hours
  • Airline
    AVIANCA AVIANCA
  • Airline alliances
    Star Alliance
  • Cabins
    Economy Business
  • Hub airports
    MDE (Secondary hub.)
  • Aircraft
    Airbus A320 and Airbus A320neo

Route FAQ

AVIANCA operates non-stop flights from MDE to GYE with 3 weekly departures.

Scheduled flight time from MDE to GYE ranges from 1 hour and 55 minutes to 2 hours. The route covers 653 miles (1051 km).

3 weekly departures are currently scheduled on this route, departing at 16:50.

Economy and Business are currently scheduled on non-stop flights for this route.
Direct flights from Medellin to Ecuador
From Medellin to Quito

UIO Mariscal Sucre International
SPONSORED AD
SPONSORED AD