Direct flights from Madrid to Istanbul
All flights from MAD to IST non-stop. There are direct flights from Barajas, Spain to Istanbul Airport (IST), Turkey every day of the week with Turkish Airlines and Air Europa. The flight distance is 1688 miles and the trip usually takes about 4 hours and 15 minutes.
Airlines with non-stop routes:

Turkish Airlines

Air Europa
Flight schedule from Madrid to Istanbul with Turkish Airlines
This is a weekly direct flight schedule for Turkish Airlines. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.
Flight
The timetable & schedule information was updated at 2025-05-15
Flight schedule from Madrid to Istanbul with Air Europa
This is a weekly direct flight schedule for Air Europa. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.
Flight
The timetable & schedule information was updated at 2025-05-15
Madrid to Istanbul flight departures
Select a date to see all scheduled flight departures between MAD to IST.

MAD - IST information
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Distance1688 miles (2716 km)
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Flight time4 hours and 15 minutes
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Airlines
Turkish Airlines
Air Europa
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AlliancesOne WorldSky TeamStar Alliance
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ClassesEconomyBusinessFirst Class
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Turkish Airlines AircraftsAirbus A318 / A319 / A320 / A321Airbus A330Boeing 737 Passenger
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Air Europa AircraftBoeing 787
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Departure TerminalTerminal 1 (Turkish Airlines)
Direct flights from Madrid to Turkiye

From Madrid to Istanbul
SAW Istanbul Sabiha Gökçen International Airport
From Madrid to Izmir
ADB İzmir Adnan Menderes Airport