Direct flights from Charlotte to Key West
All flights from CLT to EYW non-stop. There are direct flights from Charlotte Douglas International (CLT), North Carolina, USA to Key West International (EYW), Florida, USA with American Airlines. 20 weekly departures are currently scheduled on this route. Departure times range from 08:55 to 20:23 depending on the schedule period. The flight distance is 742 miles (1194 km). Flight time ranges from 2 hours and 10 minutes to 2 hours and 36 minutes.
Charlotte
, USA
Flight schedule from Charlotte to Key West with American Airlines
This is a weekly direct flight schedule for American Airlines. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.
Flight
The timetable & schedule information was updated at 2026-06-29
Charlotte to Key West scheduled departures
Select a date to see every published non-stop departure between CLT and EYW.
CLT - EYW route facts
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Distance742 miles (1194 km)
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Flight time2 hours and 10 minutes to 2 hours and 36 minutes
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Airline American Airlines
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Airline alliancesoneworld
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CabinsEconomy First
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Hub airportsCLT
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AircraftAirbus A319 and Embraer 175
Route FAQ
Direct flights from Charlotte to FL, USA
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MIA Miami International
From Charlotte to Vero Beach
VRB Vero Beach Muni
From Charlotte to Fort Lauderdale
FLL Fort Lauderdale Hollywood International
From Charlotte to Naples
APF Naples Muni
From Charlotte to Fort Myers
RSW Southwest Florida International Airport
From Charlotte to Sarasota
SRQ Sarasota Bradenton International Airport
From Charlotte to West Palm Beach
PBI Palm Beach International
From Charlotte to Pensacola
PNS Pensacola Rgnl
From Charlotte to Melbourne
MLB Melbourne International
From Charlotte to Orlando
MCO Orlando International
