Direct flights from Cleveland to Saint Louis
All flights from CLE to STL non-stop. There are direct flights from Cleveland Hopkins International (CLE), Ohio, USA to Saint Louis Airport (STL), Missouri, USA with Southwest Airlines. 13 weekly departures are currently scheduled on this route. Departure times range from 06:20 to 21:20 depending on the schedule period. The flight distance is 489 miles (787 km). Flight time ranges from 1 hour and 30 minutes to 2 hours.
Flight schedule from Cleveland to Saint Louis with Southwest Airlines
This is a weekly direct flight schedule for Southwest Airlines. Use the arrows or click on the date to change week. Click on any flight departure time to show more information and check availability.
Flight
The timetable & schedule information was updated at 2026-07-13
Cleveland to Saint Louis scheduled departures
Select a date to see every published non-stop departure between CLE and STL.
CLE - STL route facts
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Distance489 miles (787 km)
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Flight time1 hour and 30 minutes to 2 hours
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Airline
Southwest -
Airline alliancesLow-cost carrier
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CabinsEconomy
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Arrival terminalsTerminal 2
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AircraftBoeing 737-700 Passenger (Scimitar Winglets) , Boeing 737-800 (winglets) Passenger/BBJ2 and Boeing 737MAX 8 Passenger
